Electrocardiography of Laboratory Animals, 2nd Edition

Publication Year: 2019

Author / Editor: Jeffrey W. Richig and Meg M. Sleeper

Overview: This text provides a comprehensive guide to electrocardiography in laboratory animals, focusing on its critical application in preclinical safety evaluations and drug development. It details how electrophysiological monitoring helps identify potential drug-induced cardiac toxicities and parallels human clinical trials.

Key Topics Covered:

Electrocardiography in preclinical safety studies
Drug or chemical-induced cardiac toxicities in laboratory animals
Regulatory guidance and rationale drug development
Methodologies for monitoring cardiac function and integrity noninvasively